Structure determination of transmembrane protein complexes
Title: Structure determination of transmembrane protein complexes
DNr: Berzelius-2024-311
Project Type: LiU Berzelius
Principal Investigator: Linda Johansson <linda.johansson.4@gu.se>
Affiliation: Göteborgs universitet
Duration: 2024-09-01 – 2025-03-01
Classification: 10601
Homepage: https://www.gu.se/en/research/linda-johansson
Keywords:

Abstract

The Johansson group focuses on structure and function of transmembrane protein complexes including G protein-coupled receptors and transporters. Cryo-EM is a powerful tool which allows for the successful three-dimensional structures of these protein complexes. Currently, we're pursuing about ten structure determination projects within the group and our data are collected at the SciLifeLab Cryo-EM facility and we aim to use CryoSparc through the PreSTO program to process these data.