Decoding CNS gene expression regulation
Title: Decoding CNS gene expression regulation
DNr: Berzelius-2024-273
Project Type: LiU Berzelius
Principal Investigator: Enric Llorens <enric.llorens@ki.se>
Affiliation: Karolinska Institutet
Duration: 2024-07-30 – 2025-02-01
Classification: 30105
Homepage: https://ki.se/en/research/research-areas-centres-and-networks/research-groups/systems-regenerative-neurobiology-enric-llorens-group
Keywords:

Abstract

This project aims to elucidate the mechanisms of gene regulation during spinal cord development through the integration of single-cell transcriptomics and epigenomics data. By leveraging advanced machine learning models, we will analyze the gene expression profiles and epigenetic modifications at the single-cell level. This approach allows for the identification of key regulatory genes and pathways, contributing to a deeper understanding of the molecular dynamics involved in spinal cord development.