Future proteins
Title: Future proteins
DNr: NAISS 2024/22-736
Project Type: NAISS Small Compute
Principal Investigator: Lars Arvestad <arve@math.su.se>
Affiliation: Stockholms universitet
Duration: 2024-06-01 – 2025-06-01
Classification: 10203
Keywords:

Abstract

Thanks to modern prediction tools, AlphaFold in particular, the structures of a large part of the world's proteome are relatively well understood. With that knowledge, we can start asking questions of how proteins and their structures have evolved. We will investigate the constraints on protein evolution by simulating evolution and using AlphaFold to predict their structures.