Deep learning for morphological cell profiling
Abstract
In our lab we expose cells to drugs and environmental toxicants and use the Cell Painting methodology to capture images using high-content imaging. We analyze these images using AI/MOL methods including deep neural (convolutional) networks and recurrent neural networks. We also develop new methods for live-cell imaging. Key objectives are to propose new combination treatments for different types of cancers, and to study effects of combinations of environmental toxicants.