Computational methods and data analysis for optical DNA mappings
Title: Computational methods and data analysis for optical DNA mappings
SNIC Project: SNIC 2022/5-384
Project Type: SNIC Medium Compute
Principal Investigator: Tobias Ambjörnsson <tobias.ambjornsson@thep.lu.se>
Affiliation: Lunds universitet
Duration: 2022-08-30 – 2023-09-01
Classification: 10304 10402
Homepage: http://home.thep.lu.se/~tobias/index.html
Keywords:

Abstract

Optical DNA mapping is a fast way of providing gene information, full coarse-grained sequence and lengths of single DNA molecules. My theory group brought this method to applications together with several experimental partners. We are now bringing the optical DNA mapping technology to a high-throughput setting, which requires large computational resources. In this project we will assemble optical DNA mapping data from of the order 1 million DNA molecules. We will also match optical DNA mappings to theory databases.