Title:	ProteinSequenceGeneration
DNr:	Berzelius-2022-166
Project Type:	LiU Berzelius
Principal Investigator:	Tobias Karlsson <tobiaka@chalmers.se>
Affiliation:	Chalmers tekniska högskola
Duration:	2022-09-01 – 2023-03-01
Classification:	10203
Homepage:	https://psolsson.github.io/team
Keywords:

Abstract

PhD thesis work regarding development of generative, probabilistic models for protein sequences with application in protein and biologics design. More specifically, to devise a machine learned, computational framework for optimization and design of antibodies. The framework will leverage ideas from natural language processing, data from next-generation sequencing technologies and molecular simulations, as well as inductive biases from chemistry and physics.