Electrochemical oxidation of the phosphines
Title: Electrochemical oxidation of the phosphines
SNIC Project: SNIC 2020/13-50
Project Type: SNIC Small Compute
Principal Investigator: Anna Arkhypchuk <anna.arkhypchuk@kemi.uu.se>
Affiliation: Uppsala universitet
Duration: 2020-06-08 – 2021-07-01
Classification: 10405
Keywords:

Abstract

The application of an electrochemical potential to molecules is a well-known method for interfering with an organic system. The thereby formed anion or cation radicals can engage in chemical reactions with surrounding molecules, leading to the formation of new products that, crucially, would not be accessible from the reagent neutral forms. The field of chemistry that deals with such reactions is known as electro-organic synthesis, or electrochemically assisted organic chemistry. In general, electro-organic synthesis is considered to be a greener, more sustainable, and a more environmentally friendly way of performing chemical transformation since it requires less reagents and generates less waste. Despite all of the advantages of electro-organic synthesis, it has only very sporadically been applied to transformations involving main group elements such as phosphorus. The goal of the project is to electrochemically drive the resolution of racemic phosphorus mixtures into pure isomers via electrochemical oxidation of phosphorus compounds bearing chiral substituents.